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Opill OTC vs other birth control pills: What's the difference?

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 22, 2023.

Official answer

by Drugs.com

Opill is a progestin-only pill, which makes it different from other birth control pills that contain both estrogen and a progestin (such as Yaz, Junel FE, Lutera, or Sprintec) although you can get progestin-only pills (such as Cerazette, errin, and Heather) on prescription. Progestin-only pills are often called mini-pills, so Opill is a type of mini-pill.

Is Opill as effective as other birth control?

Progestin-only pills, including Opill, may have a slightly lower effectiveness compared to combination estrogen/progestin pills. To enhance their efficacy, it is recommended to take them consistently at the same time each day or within a 3-hour window of the same time daily. Progestin-only pills are often chosen for birth control by individuals who cannot take estrogen, including those who are breastfeeding.

How does Opill work?

Opill prevents conception in several different ways:

  • Thickening cervical mucus to inhibit sperm penetration
  • Lowering the midcycle LH and FSH peaks
  • Slowing the movement of the egg through the fallopian tubes
  • Altering the lining of the endometrium
  • Suppressing ovulation in approximately half of the menstrual cycles of females who use it.
References
  • Opill Tablets https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017031s035s036lbl.pdf

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